Trial design and governance

TRIAD is a multicentre, registry-nested, cluster randomised crossover trial at hospital level.

Sponsor: Australian National University
Coordination: Australian Orthopedic Association Clinical Trials and Analytics Unit
Funding: Medical Research Future Fund
Registration: ACTRN12626000076370p

Ethics approval was granted by Sydney Local Health District HREC (RPAH Zone), reference X26-0020, HREA 2025/ETH02793, with final approval dated 12 March 2026.

The study uses registry-linked outcomes together with PROMs collected before surgery and at 3, 6, and 12 months.